Windows 2000Windows XPWindows VistaWindows 7Windows 8 / 8.1Windows 10
ME 5.50
Yes
Yes
NoNoNoNo
ME 5.60
Yes
YesNoNoNoNo
ME 5.70YesYesNoNoNoNo
ME 5.80YesYesYesNoNoNo
ME 5.90YesYesYesNoNoNo
ME 6.00YesYesYesNoNoNo
ME 6.50YesYesYesYesNoNo
ME 7.00YesYesYesYesNoNo
ME 7.50NoYesNoYesNoNo
ME 8.00NoYesNoYesNoNo
ME 8.50NoNoNoYesYesNo
ME 8.60NoNoNoYesYesNo
ME 9.00NoNoNoYesYesNo
ME 9.50NoNoNoYesYesYes
ME 9.70
NoNoNoYesYesYes
ME 9.80
NoNoNoYesYesYes


Legend: 


YES - OS Fully Supported 

YES - OS Supported with some conditions applied , please download and review the system requirement document attached


Fuente: https://emerson-mas.force.com/communities/en_US/Article/Machine-Edition-OS-Compatibility-Matrix